CV: Allen D Seftel MD

Allen D Seftel, MD
Professor
Department of Urology
University Hospitals
School of Medicine
Case Western Reserve University

Answers questions in the following forums:

NetWellness Articles associated with this Author:

Article Name Forum


Erectile Dysfunction (ED)
Erectile Dysfunction (ED)


Treatment for Erectile Dysfunction
Erectile Dysfunction (ED)


Erectile Pain
Erectile Dysfunction (ED)


Premature Ejaculation: Causes and Treatment
Erectile Dysfunction (ED)

	Article Name	Forum
	Erectile Dysfunction (ED)	Erectile Dysfunction (ED)
	Treatment for Erectile Dysfunction	Erectile Dysfunction (ED)
	Erectile Pain	Erectile Dysfunction (ED)
	Premature Ejaculation: Causes and Treatment	Erectile Dysfunction (ED)

Programs:

The Urology Department at University Hospitals of Cleveland: All aspects of diagnostic and surgical urology are available for both pediatric and adult patients. Special programs include pediatric urology, urologic oncology, neurogenic bladder, spinal cord injury, renal lithiasis and lithotripsy, infertility, impotence, female urology and incontinence. Special diagnostic outpatient services include cystoscopy, cystometrics, prostate ultrasonography and plethysmography.

Education:

New York University, New York, New York, BA Chemistry, 1974 - 1978
C. W. Post College - Long Island University, Long Island, New York, Masters Biomedical Science, 1978 - 1979

Post Graduate Training:

State University of New York (SUNY) Health Science Center - Brooklyn, (formerly Downstate Medical Center), Brooklyn, New York, 1980 - 1984; M.D.
North Shore University Hospital, Manhasset, New York, PGY-1,2 - Surgery
State University of New York (SUNY) Health Science Center, Brooklyn, (formerly Downstate Medical Center), Brooklyn, New York, Urology - PGY 3
Case Western Reserve University, Cleveland, Ohio, Urology, PGY-4,5,6
American Foundation of Urologic Disease, Scholar in Impotence, Boston University School of Medicine, Boston, MA

Licensure or Certification:

Board Certified in Urology - 2/28/1995
National Board of Medical Examiners, 1985
New York State Medical License: 1985
Ohio State Medical License: 1988

Associations:

Cleveland Urological Society, President, 1996 - 1998
American Geriatric Society, National Site for Geriatric Urology, 1998
American Urological Association, North Central Section, Scientific Advisor, 1997
Cleveland Urological Society, Secretary/Treasurer, 1994 - 1996
Ohio Urologic Association, Executive Committee

Partial List of Publications:

Ziats NP, Abdul-Karim FW, Ferguson K, Hunt A, Rutchik SD, Hoffman D, Seftel AD: Upregulation of TGBF expression and decreased BFGF expression in human varicoceles. Submitted J Urol 1999.
Seftel AD, Ganz MB, Altman A, et al: High glucose concentration downregulates eNOS synthesis in human corpus cavernosal smooth muscle cells. J Urol 1999.
Ganz M, Seftel AD: Hyperglycemic induced changes in protein kinase C and nitric oxide are prevented by Vitamin E. Submitted Am J Physiology 1999.
Seftel AD, MacLennan GT, Chen A-J, Liu S, Ferguson K, Altman A, Hampel N, Ho-Chang C: Reactive oxygen species formation in diabetic male erectile dysfunction. Submitted Intl J Impotence Res 1999.
Rutchik S, Seftel AD, et al: Comparison of penile vascular testing and ambulatory nocturnal penile tumescence testing monitoring for erectile dysfunction. Submitted Intl J Impot Res 1999.
Christopf, Seftel AD, et al: Efficacy of Sildenafil (Viagra) in men with venous leak. Submitted J Urol 1999.
Seftel AD, MacLennan GT, Chen Z-J, et al. Loss of TGF beta, Apoptosis, BCL-2 in erectile dysfunction and upregulation of P53 and HIF - 1a in diabetes-associated erectile dysfunction. Accepted Molecular Urol 1999.
Ricchiuti VA, Haas CA, Seftel AD, et al. Pudendal nerve injury associated with avid bicycling. Accepted J Urol 1999.
Brown SL, Seftel AD, et al: Vasculogenic impotence and cavernosal oxygen tension. Accepted Intl J Impotence Res 1999.
Altman AL, Seftel AD, Brown SL, Hampel N: Cocaine associated priapism. J Urol 1999 June; Vol 161:1817-1818.
Kahan SE, Seftel AD, Resnick MI: Postmortem sperm procurement: Legal perspective. J Urol 1999 June;161:1840-1843.
Althof SE, Corty EW, Levine SB, Levine F, Burnett AL, McVary K, Stecher V, Seftel AD: Edits: development of questionnaires for evaluating satisfaction with treatments for erectile dysfunction. Urology 1999;53:793-799.
Paik MI, MacLennan GT, Seftel AD: Embolic testicular infarction secondary to nonbacterial thrombotic endocarditis in Wegener's granulomatosis. J Urol 1999;161:919-920.
Bodner DR, Haas CA, Krueger B, Seftel AD: Intaurethral alprostadil for treatment of erectile dysfunction in spinal cord injury patients. Urology 1999;53(1):199-202.
Rosenberg SK, Tewari R, Boswell MV, Thompson G, Seftel AD: Superior hypogastric plexus block successfully treats severe penile pain after transurethral resection of the prostate. Regional Anesthesia and Pain Medicine. Reg Anesth Pain Med 1998 Nov-Dec;23(6):618-20.
Brown SL, Haas CA, Koehler M, Bodner DR, Seftel AD: Hepatotoxicity related to intracavernous pharmacoltherapy with papaverine. Urology 1998 Nov.;52:844-847.
Seftel AD, Haas CA, Brown SL, Herbener TH, Sands M, LiPuma J: High-flow priapism complicating veno-occlusive priapism. J Urol 1998 Apr.;159(4):1300-1301.
Haas CA, Seftel AD, Razmjouej K, Ganz MB, Hampel N, Ferguson K. Erectile Dysfunction in aging: upregulation of endothelial nitric oxide synthase. Urology 1998 Mar.;51(3):516-522.
Stovsky, M, Seftel AD, Mulcahy JD, Bianchi G, Hampel N, Stroup RT. Infectious complication of penile prosthesis surgery in a diabetic man. Infections in Urology 1998 Jan./Feb.; Vol 10; 20-22.
Seftel AD, Haas CA, Vafa A, Brown SL. Inguinal-scrotal incision for penile fracture. J Urol 1998 Jan.;159(1):182-184.
Seftel AD, Vaziri ND, Ni Z, Razmjouei K, Fogarty J, Hampel N. Polak J, Wang RZ, Ferguson K, Block C, Haas C: Advanced glycation end-products in human penis: elevation in diabetic tissue, site of deposition and possible effects through iNOS or eNOS. Urology 1997 Dec.;50: 1016-1026.
Seftel AD, Rutchik SD, Chen H, Stovsky M, Goldfarb J, Desai N. Effects of subinguinal varicocele ligation on sperm concentration, motility and Kruger morphology. J Urol 1997 Nov.;156:1800-1803.
Sandock DS, Seftel AD, Resnick MI: Adrenal metastasis from renal cell carcinoma: role of ipsilateral adrenalectomy and definition of stage. J Urol 1997;49:28-31.
Seftel AD: Guest Editorial: Impotence - The paradigm shifts but the challenges remain. J Urol 1997 Nov;158:1768-69.
Seftel AD: Letter to the Editor. J Androl 1997;18:110-115.
Seftel AD: Letter to the Editor. J Androl 1997;18:110-115.
Seftel AD, Haas CA, Sweeney PJ: Hepatitis C virus: implications for the urologist. Infections in Urology 1997 Sept./Oct.;10(5):139-140.
Seftel AD, Haas C, Sweeney P: Hepatitis C and the urologist. Infections in Urology 1997 Sept. 10(5):139-140.
Carlin BI, Seftel AD, Resnick MI, Findlay J: Finasteride induced gynecomastia. J Urol 1997 Aug.;158:547.
Sutherland SE, Reigle MD, Seftel AD, Resnick MI: Protease inhibitors and urolithiasis. J Urol 1997 July;158:31-33.
Sandock DS, Seftel AD, Resnick MI: The role of gamma-glutamyl transpeptidase in the preoperative metastatic evaluation of renal cell carcinoma. J Urol 1997 Mar;157:798-799.
Sandock DS, Seftel AD, Resnick MI: Adrenal metastases from renal cell carcinoma: role of ipsilateral adrenalectomy and definition of stage. Urology 1997 Jan;49(1):28-31.
Sandock DS, Seftel AD, Herbener TE, Goldstein I, Greenfield AJ: Perineal abscess after embolization for high-flow priapism. Urology 1996;48:308-311.
Seftel AD, Matthews LA, Smith MC, Willis J. Polyoma mimicking high grade transitional cell carcinoma. J Urol 1996 Nov.;156:1764.
Seftel AD, Matthews LA, Herbener TE, Spirnak P: Corpus cavernosum-spongiosum fistula after blunt pelvic trauma: successful resolution with Digoxin. J Urol 1996 November;156:1769.
Seftel, AD. Letter to the Editor: Intracorporeal phenylephrine in the treatment of priapism, J Urol 1996;156:483.
Seftel AD, Viola KA, Kasner SE, Ganz MB. Nitric oxide relaxes rabbit corpus cavernosum smooth muscle via a potassium-conductive pathway J BBRC 1996;219:382-387.
Sandock DS, Seftel AD, Resnick MI. A new protocol for the follow-up of renal cell carcinoma based on pathological stage J Urol 1995 July;154:28-31.
Jiann D, Seftel AD et al. Age-related increase of an advanced glycation end-product in penile tissue: potential role in erectile dysfunction J Urol 1995;13:369-75.
Seftel AD, Herbener TE, Becker M, Aron D, Resnick MI: Focal inflammation of the corpus cavernosum in a diabetic man due to acute occlusion of the cavernous artery: J Urol 1995;May 153:1622-1624.
Stovsky MD, Seftel AD, Resnick MI: Delayed hypersensitivity reaction after infusion of non-ionic intravenous contrast material for an excretory urogram: a case report and review of the literature. J Urol 1995 May;153:1641-1643.

Hospital Appointments:

Associate Professor, Department of Urology, Case Western Reserve University, 1998 - Present
Associate Professor, Department of Reproductive Biology, Case Western Reserve University

Grants:

Clinical Research Grants
Ultrasound Prostate Cancer Network: Transrectal Prostate Ultrasound Prior to Cystoprostatectomy for Treatment of Carcinoma of the Bladder. NIH Grant, co-investigator, October 1989 to present.
Ultrasound Prostate Cancer Network: Transrectal Ultrasonography of the Prostate Prior to Transurethral Resection for Presumed Benign Prostatic Hyperplasia. NIH Grant, co-investigator, October 1989 to present.
Ultrasound Prostate Cancer Network: Determination of Ultrasonography Characteristics of Adenocarcinoma of the Prostate and the Accuracy of Ultrasonography compared to Digital Rectal Examination in Staging Apparently Localized Carcinoma of the Prostate. NIH Grant, co-investigator, October 1989 to present.
Basic Science Research Grants
1997 - 2000 Arthur Sullivan Foundation: $210,000; Role of nitric oxide on prostatitis, Principal Investigator
1997 - 2001 Veterans Administration Central Office: $269,400 Merit Review Grant, Penile advanced glycation end-products produce impotence in aging men - Principal Investigator
1994 - 1997 Veterans Administration Central Office: $146,000 - Merit Review Grant, Penile advanced glycation end products produce impotence in aging men - Principal Investigator
1995 - 1996 American Federation for Aging - Ohio Affiliate: $7,500 Impotence in aging men - Principal Investigator
1995 - 1996 Ohio Regents: $5,000 The Role of Potassium Channels in Corpus Cavernosum Smooth Muscle Cell Relaxation - Principal Investigator
1994 - 1995 Community Dialysis Center - Rosenberg Foundation: $20,000, Effects of Aging on Male Sexual Function - Principal Investigator
1993 - 1994 Claude Pepper / John Hartford - Foundation for Agency Research: $5,000, Effects of Aging on Male Sexual Function - Principal Investigator
1993 - 1994 National Kidney Foundation - Young Investigator Award: $20,000, Physiologic Role of Penile Microvasculature in Erection: Principal Investigator
1992 - 1993 National Kidney Foundation - Young Investigator Award: $20,000, Physiologic Role of Penile Microvasculature in Erection: Principal Investigator

Awards:

Teaching Excellence Award - Residents in the Department of Family Medicine - 1999
Pfizer Scholar in Urology, 1997
SUNY Health Science Center - Brooklyn, Instructor in Anatomy, Summer 1981