CV: Susan Moffatt-Bruce MD, PhD

Susan Moffatt-Bruce, MD, PhD
Assistant Professor
Division of Cardiothoracic Surgery
Department of Surgery
College of Medicine
The Ohio State University

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Education:

University of Cambridge, Cambridge, United Kingdom, Ph.D. Transplantation Immunology, 1999.
Dalhousie University, Halifax, Nova Scotia, Canada, Doctorate of Medicine, 1994.
McGill University, Montreal, Quebec, Canada, Bachelor of Science, 1990. Biochemistry Honors Program, University Scholar

Post Graduate Training:

Stanford University, Palo Alto, California, Chief Resident in Cardiothoracic Surgery, Thoracic Transplantation/Ventricular Assist Surgery, July 2001-July 2004.
Dalhousie University, Halifax, Nova Scotia, Canada, Resident in General Surgery, June 1994-June 2001.

Licensure or Certification:

LICENSURE: Ohio, California, British Columbia, Canada

Associations:

Royal College of Physicians and Surgeons of Canada
Society of Thoracic Surgeons
American College of Surgeons
American Society of Transplantation
International Society of Heart and Lung Transplantation
British Transplantation Society
The Transplantation Society (World)
The Canadian Transplantation Society
Fellow of the Cambridge Commonwealth Society
Alpha Omega Alpha Honor Medical Society
Columbus Medical Association
Ohio State Medical Association
American Thoracic Society

Affiliations:

The Ohio State University Hospitals, Assistant Professor of Surgery, Division of Cardiothoracic Surgery, Columbus, Ohio July 2006-present.
University of British Columbia, Clinical Instructor/Staff Surgeon, Vancouver, British Columbia, Canada, July 2004-June 2006.

Partial List of Publications:

Are Heart-Lung Transplant Recipients Protected from Developing Bronchiolitis Obliterans Syndrome?, Moffatt-Bruce SD, Karamichalis J, Robbins RC, Theordore J, Whyte RI, Reitz BA. Annals of Thoracic Surgery 2006; 81:286-91.
Early Antithrombotic Therapy for Aortic Valve Bioprostheses: Is There an Indication for Routine Use? Jamieson WRE, Moffatt-Bruce SD, Skarsgard Peter et al. Annals of Thoracic Surgery, 2006 accepted.
Thoracic Aortic Aneurysms. Moffatt-Bruce SD, Mitchell RS. Surgery: Scientific Principles and Practice, edited by Drs. Mulholland, Lillemoe, Doherty, Maier and Upchurch. Lippincott Williams &Wilkins 2006.
Heart-Lung Transplantation: Is it a Viable Option in the 21st Century?, Moffatt-Bruce SD, Reitz BA. Lung Biology in Health and Disease, edited by JP Lynch and DJ Ross. Marcel Dekker Inc.2006.
Lung and Heart-Lung Transplantation, Moffatt SD, Reitz BA. The Johns Hopkins Manual of Cardiothoracic Surgery, Yuh, Vricella, Baumgartner, 1st Edition, McGraw-Hill, 2006.
Endovascular Therapy for the Treatment of Thoracic Aortic Disease, Moffatt-Bruce SD, Mitchell RS. Cardiac Surgery in the Adult. 3rd Edition, Eds. Cohn and Edmunds, 2006 in press
Lung Transplantation, A Decade of Experience, Moffatt SD, Demers P, Robbins RC, Doyle R, Henig N, Theordore J, Reitz BA, Whyte RI. J Heart Lung Transplant 2005; 24: 145-51.
Surgical Treatment of Heart Failure, Cardiac Transplantation and Mechanical Ventricular Support, Moffatt SD, Robbins RC. Hurst’s The Heart, 11th Edition, 2005
Long Term Performance of Protheses in Mitral Valve Replacement, Moffatt-Bruce SD, Jamieson WRJ. Journal of Cardiovascular Surgery, 2004; 45: 427-47.
Cardiac Transplantation and Long-Term Mechanical Circulatory Support, Kouretas, P, Moffatt-Bruce SD, Robbins RC. Heart Failure: A Comprehensive Guide to Diagnosis and Management, Editors GW Dec. Assoc Editors T DiSalvo, RJ Hajjar, M Semigram. 2004.
Long-Term Results of Heart Transplantation in Patients Aged 60 Years and Older, Demers P, Moffatt S, Oyer PE, Hunt SA, Reitz BA, Robbins RC. JTCVS 2003; 126: 224.
Chronic Expanding Hematoma of the Thorax, Hwang GL, Moffatt SD, Mitchell JD, Leung AN. AJR 2003; 180: 1182.
Endovascular Stent Management of Thoracic Aneurysms and Dissections, Moffatt SD, Mitchell RS. Cardiac Surgery in the Adult. 2nd Edition, Eds. Cohn and Edmunds, 2003.
The Role of VATS and Classical Thoracotomy in Lung Cancer Management, Moffatt SD, Mitchell JD. Current Opinion in Pulmonary Medicine, 2002; 8(4).
Massive Pleural Endometriosis. Moffatt SD, Mitchell JD. Eur J Cardiothorac Surg 2002; 22: 321.
An ex vivo model of tolerance versus rejection: Comparison of STAT1, STAT4, STAT5, STAT6 Metcalfe SM & Moffatt-Bruce SD. Clinical Chemistry and Laboratory Medicine 2001; 38(11): 1195.
Prope Tolerance with Induction using Campath 1H and Low-dose Cyclosporine Monotherapy in 31 Cadaveric Renal Allograft, Recipients: Calne R, Moffatt SD, Friend PJ, Jamieson NV, Bradley JA, Hale G, Firth J, Bradley J, Smith KG. Nippon Geka Gakkai Zasshi 2000; 101(3): 301.
Comparison between tacrolimus and cyclosporine as immunosuppresive agents compatible with tolerance induction by CD4/CD8 blockade, Moffatt SD, Metcalfe SM. Transplantation 2000; 69:1724.
STAT6 Upregulation by FK506 in the Presence of IL4, Moffatt SD, Cockman M, Metcalfe SM. Transplantation 2000; 69:1521.
Allo-tolerance and alloreejection responses ex vivo. Moffatt SD, Metcalfe S. Transplant International 2000; 13: 474.
The Comparative Efficacy of Liposomal FK506 with FK506 with and without AntiCD4/CD8 Monoclonal Antibodies, Moffatt SD, McAlister V, Calne RY, Metcalfe SM. Transplantation Proceedings 1999; 31: 2754.
FK506 Versus Cyclosporin A in Combination with AntiCD4/CD8 Monoclonal Antibodies, Moffatt SD, Metcalfe SM. Transplantation Proceedings 1999; 31: 2740.
Potential for Improved Therapeutic Index of FK506 in Liposomal Formulation demonstrated in a Mouse Cardiac Allograft Model, Moffatt SD, McAlister V, Calne RY, Metcalfe SM. Transplantation 1999; 67: 1205.
The Comparison of Methods to Induce Tolerance in a Cardiac Transplantation Model, Moffatt SD, Metcalfe SM. Clinical and Investigative Medicine 1998; 21(4)S: 3.
Perioperative Campath 1H and Low Dose Cyclosporin Monotherapy in Liver and Renal Allograft, Recipients, Calne R, Friend P, Moffatt S, Bradley A, Hale G, Firth J, Bradley J, Smith K, Waldmann H. Lancet 1998; 351: 1701.
Comparative Efficacy of Liposomal FK506 with FK506, Moffatt SD, McAlister V, Calne RY, Metcalfe SM. Transplantation Proceedings 1998; 30: 4066

Research:

Use of Induction Therapy in Lung Transplantation Bridge to Heart Transplantation using LVAD or Inotropic Support
Immunosuppression Conversion Rates and Outcomes of Heart and Lung Transplant Recipients
Immunological profile of the mouse atherosclerotic transplant model after immunomodulation
Induction of Transplantation Tolerance in a Mouse Heart Allograft Model: Identification of Surrogate Markers
PROPE Tolerance: CAMPATH in Renal and Hepatic Transplantation

Grants:

RESEARCH FUNDING: College of Medicine Research Investment Fund $55,000 for one year, possible renewal for 2 additional years

Partial List of Presentations:

Immunoprofiling in Transplantation, Moffatt-Bruce, SD , Comprehensive Transplant Center Lecture Series, Ohio State University Medical Center, September 2006
Intermediate Term Performance of Bioprostheses in Mitral Valve Replacement Abdel Hadi M, Jamieson WRE, Moffatt-Bruce SD et al. Third Biennial Meeting for the Society of Heart Valve Disease, Vancouver, June 2005
Anticoagulation for Aortic Valve Bioprosthesis: A Time to Reconsider Moffatt-Bruce SD, Jamieson WRE, Abdel Hadi M et al. Third Biennial Meeting for the Society of Heart Valve Disease, Vancouver, June 2005.
“The 80 Hour Work Week: How it is affecting Thoracic Surgery Residencies” Moffatt-Bruce SD. American College of Surgeons, New Orleans, October 2004
Improved Heart Transplant Survival in Patients Bridged with Ventricular Assist Device, MC Chan, S Moffatt, ES Shao, B Cantin, M Pelletier, P Oyer, RC Robbins, SA Hunt, ISHLT, San Francisco, April 2004
Are Heart-Lung Transplant Recipients Protected from Developing Bronchiolitis Obliterans Syndrome?, Moffatt-Bruce SD, Karamichalis J, Robbins RC, Theordore J, Whyte RI, Reitz BA. Society of Thoracic Surgeons, San Antonio Texas, January 2004
Surgical Options for End-Stage Heart Failure, Adult Critical Care: Cardiothoracic Surgical Interventions, Stanford University, June 2003
Bridge to Cardiac Transplantation: Comparison of LVAD versus Inotropic Support, ISHLT, Vienna, Austria, April 2003
Conversion from Cyclosporin to Tacrolimus in Double Lung and Heart-Lung Transplant Recipients, British Transplantation Society Meeting, London, April 2003
The Use of Older Donors in Heart Transplantation, British Transplantation Society Meeting, London, April 2003
Determinants of Early and Late Survival After Heart Transplantation: A 20-Year Experience in the Cyclosporine Era, P Demers, S Moffatt-Bruce, Canadian Cardiovascular Society Meeting, Toronto, 2003
Bridge to Cardiac Transplantation: Comparison of LVAD versus Inotropic Support American Heart Association, Chicago, November 2002
Combined Heart-Lung Transplantation for Primary and Secondary Pulmonary Hypertension American Heart Association, Chicago, November 2002
Lung Transplantation: A Decade of Experience- Western Thoracic Surgical Society Meeting, Big Sky, Montana, June 2002
Active Transplantation Tolerance ex vivo: STAT levels and Cytokine Secretion- British Transplantation Society Conference, Oxford, March 2001
Tolerance Induction in a Cardiac Transplant Model- Canadian Cardiovascular Society Conference, Vancouver, November 2000
Immunosuppressants: Past, present and future- The Canadian Kidney Foundation Transplantation 2000, Ottawa, Ontario, April 2000
Operational Tolerance to Mouse Heart Allografts: Vessel Histology Following CD4/CD8 blockade alone and in combination with immunosuppressive drugs- British Transplantation Society Conference, Cardiff, Wales, March 2000
An Immunological Review of Transplantation- University of Ottawa Heart Institute, Ottawa, Ontario, November 1999
STATS in Murine Allo-Tolerance and Allo-Rejection responses ex vivo. – American Society of Transplantation 18th Annual Meeting, May 1999.
Upregulation of STAT6 by IL-4 in the Presence of FK506- British Transplantation Society Conference, Edinburgh, Scotland, March 1999
The Comparison of Methods to Induce Tolerance in a Cardiac Transplantation Model- Royal College of Physicians and Surgeons of Canada Annual Meeting, Toronto, Ontario, October 1998
Comparative Efficacy of Liposomal FK506 with FK506 with and without AntiCD4+/CD8+ Monoclonal Antibodies- The International Alexis Carrel Conference, Kyoto, Japan, October 1998
Comparative Efficacy of Liposomal FK506 with FK506- World Congress of the Transplantation Society, Montreal, Quebec, July 1998
Comparative Efficacy of Liposomal FK506 with FK506 with and without Anti-CD4+/CD8+ Monoclonal Antibodies- British Transplantation Society Meeting, Dublin, Ireland, April 1998
Comparative Efficacy of Liposomal FK506 with FK506- 3rd International Conference on New Trends in Clinical and Experimental Immunosuppression, Geneva, Switzerland, February 1998
FK506 versus Cyclosporin A in Combination with Anti-CD4+/CD8+ Monoclonal Antibodies- The International Alexis Carrel Conference, Kyoto, Japan, October 1998

Awards:

2002. Samson Resident Research Essay Prize, Western Thoracic Surgical Association
1998-1999. Sackler Scholarship, University of Cambridge
1998. British Transplantation Society, Research Award
1998. Bayer-Canadian Association of Allergy and Clinical Immunology Research Award
1997-1999. Canadian Association of General Surgeons, Academic Research Award
1997-life. Fellow of the Cambridge Commonwealth Society
1996-1999. NATO Collaborative Research Award
1996-1999. Cambridge Commonwealth, Trust Bursary Award
1996-1999. Overseas Research Student Award- University of Cambridge
1996-1999. Killam Postgraduate Research Award Dalhousie University
May 1994. Doctor of Medicine with Distinction
August 1992. Elected to Alpha Omega Alpha Honor Medical Society
1991-1993. Dalhousie University Scholarship for High Academic Standing
1986-1990. McGill University Scholar

Answers questions in the following forums:

NetWellness Articles associated with this Author:

Education:

Post Graduate Training:

Licensure or Certification:

Associations:

Affiliations:

Partial List of Publications:

Research:

Grants:

Partial List of Presentations:

Awards:

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