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NetWellness provides the highest quality health information and education services created and evaluated by faculty of our partner universities.
Sunday, September 7, 2008
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NetWellness provides the highest quality health information and education services created and evaluated by faculty of our partner universities.
Sunday, September 7, 2008
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Cancer |
Blood marrow donor06/10/2008 03:56PM |
Can your children be your blood marrow donors?
Usually, children are not the best bone marrow donors; the best donor would be an identical twin, which very few of us have. On chromosome 6, there is the human leukocyte antigen (HLA) gene and within that gene are two copies of 3 major proteins (A, B, DR). Everyone gets a set of A, B, and DR from each parent. There is a 25% chance that one of your siblings will be perfectly matched to you and a 0% that your children will be matched perfectly to you as they have a set of the other parents' A, B, DR. The closer the match, the better the outcome for the patient in regards to lifespan, time to recover bone marrow function, and side effects. Talk to your physician about the risk of related, but unmatched donors and non-related, but A, B, DR matched donors.
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Joanna M Brell, MD Assistant Professor Division of Hematology/Oncology Ireland Cancer Center University Hospitals School of Medicine Case Western Reserve University |
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