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NetWellness provides the highest quality health information and education services created and evaluated by faculty of our partner universities.
Saturday, March 20, 2010
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NetWellness provides the highest quality health information and education services created and evaluated by faculty of our partner universities.
Saturday, March 20, 2010
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High Blood Pressure |
ARB tablets09/29/2009 |
Dear doctor,I have been considering trying out an ARB but was wondering which type is better, candesartan, losartan or olmesartan. My understanding is that olmesartan and losartan are better. I also find myself in a predicament in that after continuous use of most medication, I start getting some sort of asthma like breathing problems. I am a mild asthmatic . Are there any medications which are suitable for asthmatics and well tolerated?
Thanks.
There is very little difference between candesartan, losartan and olmesartan. Although they are different molecules, they work by the same mechanism and there should be no noticeable difference in their clinical effects and side effects. Exceptions and allergic reactions are possible, but rare.
Regarding asthma, the only anti-hypertensive drugs that are contra-indicated are beta blockers. None of the other agents have an effect on bronchoconstriction.
If you have difficulty with an ARB, you may try a direct renin inhibitor (aliskiren). Aliskiren is very well tolerated and has not been found to worsen asthma.
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Max C. Reif, MD Director, Hypertension Section Division of Nephrology & Hypertension Department of Internal Medicine College of Medicine University of Cincinnati |
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